Population Genetics Simulation

This is the number of individuals, N, per generation in the simulation. Note, the number of chromosomes is 2N. If this parameter is not enabled, the simulation will model the theoretical infinitely sized population.

This parameter sets the number of simulations that will be run and plotted simultaneously as a batch.

This describes the relative fitness of individuals with the AA genotype. Higher values represent greater fitness. This coefficient is used in conjunction with the fitness coefficients of the other genotype groups (i.e., w_Aa and w_aa). Note, selection can be defined in terms of the three fitness coefficients or in terms of the selection and dominance coefficients, but not both.

This describes the relative fitness of individuals with the Aa genotype. Higher values represent greater fitness. This coefficient is used in conjunction with the fitness coefficients of the other genotype groups (i.e., w_AA and w_aa). Note, selection can be defined in terms of the three fitness coefficients or in terms of the selection and dominance coefficients, but not both.

This describes the relative fitness of individuals with the aa genotype. Higher values represent greater fitness. This coefficient is used in conjunction with the fitness coefficients of the other genotype groups (i.e., w_AA and w_Aa). Note, selection can be defined in terms of the three fitness coefficients or in terms of the selection and dominance coefficients, but not both.

This represents the degree of selection against the aa genotype group with respect to the AA genotype group. A value of s = 1 indicates 100% selection against the aa genotype group. A value of s = 0 indicates no selection against the aa genotype group. Note, selection can be defined in terms of the selection and dominance coefficients, or in terms of the three fitness coefficients, but not both.

This represents the degree of dominance of the unfavored a allele in selection. The product of selection and dominance coefficients (i.e., s × h) represents the degree of selection against the Aa genotype group with respect to the AA genotype group. A value of h = 1 indicates that the Aa genotype group is equally unfavored as the aa genotype group. A value of h = 0 indicates that the Aa genotype group is equally favored as the AA genotype group. A value of h = 0.5 represents the additive model, where the selection against the Aa genotype group is half that of the aa genotype group. Negative values of h (representing over‐dominance or “heterozygote advantage”) are not implemented. Instead use fitness coefficients to describe situations of over‐ or under‐dominance. Note, selection can be defined in terms of selection and dominance coefficients, or in terms of the three fitness coefficients, but not both.

The rate at which allele A mutates to allele a per generation.

The rate at which allele a mutates to allele A per generation.

The rate at which migrant alleles enter the population per generation.

The frequency of the A allele among all migrant alleles entering the population.

This is the probability that both alleles in a randomly chosen individual in the population are identical‐by‐descent (IBD). A value of F = 0 indicates there is no inbreeding within the population. A value of 1 indicates that there is complete autozygosity such as found in inbred lines of model organisms.

This is the excess fraction of positive assortative matings in the population where 1 ‐ α is the fraction of random matings. A value of α = 1 indicates 100% positive assortative mating, and a value of α = 0 indicates total random mating.

This is the number of individuals in the population during the bottleneck event. Note that the number of chromosomes simulated is 2NB.